Dr. Andrea Bischoff presents the audience with question poles on hirschsprung's disease diagnosis gestational age, suction rectal biopsy with absent ganglion cells, and full thickness biopsy, and permanent section versus frozen, intraoperative suction visibility, nerve measurements. Discussion is generated among panel members. Dr. Margaret H. Collins discusses the pathologists' response, including a presentation on  transition zone measurements, ganglion cells, submucosal hyperganglionosis, inconsistent diagnostic criteria, and inadequate control data.